She's My Best Friend:' Rob Lowe and Sheryl Berkoff's Relationship Photos Through the Years - PEOPLE

In 1993, the couple welcomed their first son, Matthew, into the world, followed by son John Owen in 1995. Lowe told PEOPLE, "I'm happy I lived the life that I lived because I have no regrets, but I was super ready to coach Little League, carve pumpkins on Halloween, read books and serve hot lunch on Wednesdays. I really, really loved every minute of it."
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